Article
The ADAMTS1 Gene Is Associated with Familial Mandibular Prognathism.
Journal of dental research - 1 Sept 2015
Guan X, Song Y, Ott J, Zhang Y, Li C, Xin T, Li Z, Gan Y, Li J, Zhou S, Zhou Y
Abstract excerpt
Mandibular prognathism is a facial skeletal malocclusion. Until now, the genetic mechanism has been unclear. The goal of this study was to identify candidate genes or genomic regions directly associated with mandibular prognathism development, by employing whole genome sequencing. A large Chinese family was recruited, composed of 9 affected and 12 unaffected individuals, and the inheritance pattern of this family...
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