Article
Tumour radiosensitivity is associated with immune activation in solid tumours.
European journal of cancer (Oxford, England : 1990) - 1 Oct 2017
Strom Tobin, Harrison Louis B, Giuliano Anna R, Schell Michael J, Eschrich Steven A, Berglund Anders, Fulp William, Thapa Ram, Coppola Domenico, Kim Sungjune, Frakes Jessica, Foekens John, Mulé James J, Torres-Roca Javier F
Abstract excerpt
PURPOSE: Our goal was to determine whether tumour radiosensitivity is associated with activation of the immune system across all tumour types as measured by two gene expression signatures (GESs). METHODS: We identified 10,240 genomically profiled distinct solid primary tumours with gene expression analysis available from an institutional de-identified database. Two separate GESs were included in the analysis, the...
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