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Article

Chemical genetics-based development of small molecules targeting hepatitis C virus.

Archives of pharmacal research - 1 Sept 2017

Jin Guanghai, Lee Jisu, Lee Kyeong

Abstract excerpt

Hepatitis C virus (HCV) infection is a major worldwide problem that has emerged as one of the most significant diseases affecting humans. There are currently no vaccines or efficient therapies without side effects, despite today's advanced medical technology. Currently, the common therapy for most patients (i.e. genotype 1) is combination of HCV-specific direct-acting antivirals (DAAs). Up to 2011, the standard...

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PMID: 28856597
DOI: 10.1007/s12272-017-0949-3

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