Functional proteomics outlines the complexity of breast cancer molecular subtypes.

doi:10.1038/s41598-017-10493-w

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Article

Functional proteomics outlines the complexity of breast cancer molecular subtypes.

Scientific reports - 30 Aug 2017

Gámez-Pozo Angelo, Trilla-Fuertes Lucía, Berges-Soria Julia, Selevsek Nathalie, López-Vacas Rocío, Díaz-Almirón Mariana, Nanni Paolo, Arevalillo Jorge M, Navarro Hilario, Grossmann Jonas, Gayá Moreno Francisco, Gómez Rioja Rubén, Prado-Vázquez Guillermo, Zapater-Moros Andrea, Main Paloma, Feliú Jaime, Martínez Del Prado Purificación, Zamora Pilar, Ciruelos Eva, Espinosa Enrique, Fresno Vara Juan Ángel

Abstract excerpt

Breast cancer is a heterogeneous disease comprising a variety of entities with various genetic backgrounds. Estrogen receptor-positive, human epidermal growth factor receptor 2-negative tumors typically have a favorable outcome; however, some patients eventually relapse, which suggests some heterogeneity within this category. In the present study, we used proteomics and miRNA profiling techniques to characterize...

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PMID: 28855612
DOI: 10.1038/s41598-017-10493-w
PMCID: PMC5577137

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