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Sperm chemorepulsion, a supplementary mechanism to regulate fertilization

7 Jun 2017

Abstract excerpt

STUDY QUESTION: Are human spermatozoa able of chemorepulsive behaviour? SUMMARY ANSWER: Capacitated human spermatozoa are able to be chemorepelled by synthetic Progesterone Receptor Ligands (sPRL, known as contraceptives) and zinc (a cation released by the oocyte upon fertilization). WHAT IS KNOWN ALREADY: Moving cells can be oriented towards or against a molecular gradient, processes called chemoattraction and...

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PMID: 28854585
DOI: 10.1093/humrep/dex232

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