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How the human spermatozoa sense the oocyte: a new role of SDF1-CXCR4 signalling

30 May 2011

Abstract excerpt

For fertilization to occur in mammals, ejaculated spermatozoa must reach the egg which, following ovulation has moved from the ovary into the Fallopian tube. Two active mechanisms of spermatozoa guidance have been shown in mammals: thermotaxis and chemotaxis. The identity of most of human spermatozoa chemoattractants is unknown, and herein we tested if SDF1 (chemokine stromal cell-derived factor-1) and its...

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PMID: 21623830
DOI: 10.1111/j.1365-2605.2011.01158.x

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