Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effect of APOE, CETP, and PCSK9 polymorphisms on simvastatin response in Thai hypercholesterolemic patients.

Cardiovascular therapeutics - 1 Dec 2017

Wanmasae Smith, Sirintronsopon Wisant, Porntadavity Sureerut, Jeenduang Nutjaree

Abstract excerpt

AIM: To investigate the effect of apolipoprotein E (APOE), cholesteryl ester transfer protein (CETP) and proprotein convertase subtilisin kexin type 9 (PCSK9) polymorphisms on the lipid-lowering response to simvastatin therapy in Thai hypercholesterolemic patients. METHOD: Two hundred and twenty-five hypercholesterolemic patients in southern Thailand were enrolled and treated with simvastatin 20 or 40 mg per day...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins E
Share to Cholesterol Ester Transfer Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Share to Hypercholesterolemia

Share to Lipids

Share to Proprotein Convertase 9

Share to Simvastatin

Share to Thailand

Source

Identifiers

PMID: 28851085
DOI: 10.1111/1755-5922.12302

Genes

CETP
PCSK9
APOE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effect of APOE, CETP, and PCSK9 polymorphisms on simvastatin response in Thai hypercholesterolemic patients.PMID 28851085Read ↗

Combined PCSK9 and APOE polymorphisms are genetic risk factors associated with elevated plasma lipid levels in a Thai population.Semantic proximity Read ↗

Influence of PCSK9 polymorphisms on plasma lipids and response to atorvastatin treatment in Brazilian subjects.Semantic proximity Read ↗

The influence of apolipoprotein B and E gene polymorphisms on the response to simvastatin therapy in patients with hyperlipidemia.Semantic proximity Read ↗

Association of polymorphisms of ApoE, ApoA1, PCSK9 with LDL-C modification following Atorvastatin therapy in dyslipidemic patients.Semantic proximity Read ↗

APOE gene polymorphisms and response to statin therapy.Semantic proximity Read ↗

Lack of association between SLCO1B1 polymorphisms and lipid-lowering response to simvastatin therapy in Thai hypercholesterolaemic patients.Semantic proximity Read ↗

Effect of CETP polymorphism on atorvastatin lipid-regulating effect and clinical prognosis of patients with coronary heart disease.Semantic proximity Read ↗

Cholesteryl ester transfer protein rs1532624 gene polymorphism is associated with reduced response to statin therapy.Semantic proximity Read ↗

Genetic and gender factor affect lipid profiles of patients receiving statin treatment in the east coast region of Peninsular MalaysiaSemantic proximity Read ↗

CYP3A4*1B and CYP3A5*3 SNPs significantly impact the response of Egyptian candidates to high-intensity statin therapy to atorvastatin.Semantic proximity Read ↗

The effect of genetic variation in PCSK9 on the LDL-cholesterol response to statin therapy.Semantic proximity Read ↗

[Influence of PCSK9 gene E670G polymorphism on the risk of atherosclerotic coronary heart disease and plasma lipid level].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.