Article
Immune responses in DAA treated chronic hepatitis C patients with and without prior RG-101 dosing.
Antiviral research - 1 Oct 2017
van der Ree Meike H, Stelma Femke, Willemse Sophie B, Brown Anthony, Swadling Leo, van der Valk Marc, Sinnige Marjan J, van Nuenen Ad C, de Vree J Marleen L, Klenerman Paul, Barnes Eleanor, Kootstra Neeltje A, Reesink Hendrik W
Abstract excerpt
BACKGROUND&AIMS: With the introduction of DAA's, the majority of treated chronic hepatitis C patients (CHC) achieve a viral cure. The exact mechanisms by which the virus is cleared after successful therapy, is still unknown. The aim was to assess the role of the immune system and miRNA levels in acquiring a sustained virological response after DAA treatment in CHC patients with and without prior RG-101...
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