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Article

Identification of broadly neutralizing monoclonal antibodies against Crimean-Congo hemorrhagic fever virus.

Antiviral research - 1 Oct 2017

Zivcec Marko, Guerrero Lisa I W, Albariño César G, Bergeron Éric, Nichol Stuart T, Spiropoulou Christina F

Abstract excerpt

Despite the serious public health impact of Crimean-Congo hemorrhagic fever (CCHF), the efficacy of antivirals targeting the causative agent, CCHF virus (CCHFV), remains debatable. Neutralizing monoclonal antibodies (MAbs) targeting the CCHFV glycoprotein Gc have been reported to protect mice against challenge with the prototype CCHFV strain, IbAr10200. However, due to extensive sequence diversity of CCHFV...

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Source

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Identifiers

PMID: 28842265
DOI: 10.1016/j.antiviral.2017.08.014
PMCID: PMC7195853

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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