Article
Diencephalic pediatric low-grade glioma harboring the BRAF V600E mutation presenting with various morphologies in sequential biopsy specimens.
Brain tumor pathology - 1 Oct 2017
Ishi Yukitomo, Hatanaka Kanako C, Yamaguchi Shigeru, Fujita Hiromi, Motegi Hiroaki, Kobayashi Hiroyuki, Terasaka Shunsuke, Houkin Kiyohiro
Abstract excerpt
A 5-year-old boy underwent biopsy of an intra-axial calcified tumor in the hypothalamus, which was incidentally found. Based on the presence of ganglion-like cells combined with glial cell element, the pathological diagnosis was ganglioglioma. Because the tumor grew gradually in size over the next 2 years, he underwent chemotherapy with temozolomide. However, at 8 years of age, the boy developed hydrocephalus and...
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