Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Zebrafish nephrosin helps host defence against Escherichia coli infection.

Open biology - 1 Aug 2017

Di Qianqian, Lin Qing, Huang Zhibin, Chi Yali, Chen Xiaohui, Zhang Wenqing, Zhang Yiyue

Abstract excerpt

Neutrophils play important roles in innate immunity and are mainly dependent on various enzyme-containing granules to kill engulfed microorganisms. Zebrafish nephrosin (npsn) is specifically expressed in neutrophils; however, its function is largely unknown. Here, we generated an npsn mutant (npsnsmu5 ) via CRISPR/Cas9 to investigate the in vivo function of Npsn. The overall development and number of neutrophils...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR-Cas Systems
Share to Embryo, Nonmammalian
Share to Escherichia coli Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knockdown Techniques

Share to Metalloendopeptidases

Share to Neutrophils

Share to Zebrafish

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 28835569
DOI: 10.1098/rsob.170040
PMCID: PMC5577445

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Zebrafish nephrosin helps host defence against Escherichia coli infection.PMID 28835569Read ↗

Deficiency in macrophage-stimulating protein results in spontaneous intestinal inflammation and increased susceptibility toward epithelial damage in zebrafish.Semantic proximity Read ↗

Intestinal Serum Amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonizationSemantic proximity Read ↗

Commensal microbiota stimulate systemic neutrophil migration through induction of Serum amyloid ASemantic proximity Read ↗

Functional Analysis of Two Novel Streptococcus iniae Virulence Factors Using a Zebrafish Infection ModelSemantic proximity Read ↗

The role of neutrophil typing in homeostatic resilience protective model of inflammatory preconditioningSemantic proximity Read ↗

Innate Immune Response to Streptococcus iniae Infection in Zebrafish LarvaeSemantic proximity Read ↗

Neutrophil phagocyte oxidase activity controls invasive fungal growth and inflammation in zebrafishSemantic proximity Read ↗

Infection-experienced HSPCs protect against infections by generating neutrophils with enhanced bactericidal activitySemantic proximity Read ↗

Characterization of the innate immune response to Streptococcus pneumoniae infection in zebrafishSemantic proximity Read ↗

Congenital asplenia due to a tlx1 mutation reduces resistance to Aeromonas hydrophila infection in zebrafish.Semantic proximity Read ↗

Streptococcus-Zebrafish Model of Bacterial PathogenesisSemantic proximity Read ↗

<i>Candida spp.</i> suppress neutrophil reactive nitrogen species to evade killingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.