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The differential role of reactive oxygen species in early and late stages of cancer

24 Aug 2017

Abstract excerpt

The large doses of vitamins C and E and β-carotene used to reduce reactive oxygen species (ROS) production and oxidative damages in cancerous tissue have produced disappointing and contradictory results. This therapeutic conundrum was attributed to the double-faced role of ROS, notably, their ability to induce either proliferation or apoptosis of cancer cells. However, for a ROS-inhibitory approach to be...

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PMID: 28835450
DOI: 10.1152/ajpregu.00247.2017

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