Numerous uncharacterized and highly divergent microbes which colonize humans are revealed by circulating cell-free DNA.

doi:10.1073/pnas.1707009114

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Article

Numerous uncharacterized and highly divergent microbes which colonize humans are revealed by circulating cell-free DNA.

Proceedings of the National Academy of Sciences of the United States of America - 5 Sept 2017

Kowarsky Mark, Camunas-Soler Joan, Kertesz Michael, De Vlaminck Iwijn, Koh Winston, Pan Wenying, Martin Lance, Neff Norma F, Okamoto Jennifer, Wong Ronald J, Kharbanda Sandhya, El-Sayed Yasser, Blumenfeld Yair, Stevenson David K, Shaw Gary M, Wolfe Nathan D, Quake Stephen R

Abstract excerpt

Blood circulates throughout the human body and contains molecules drawn from virtually every tissue, including the microbes and viruses which colonize the body. Through massive shotgun sequencing of circulating cell-free DNA from the blood, we identified hundreds of new bacteria and viruses which represent previously unidentified members of the human microbiome. Analyzing cumulative sequence data from 1,351 blood...

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Identifiers

PMID: 28830999
DOI: 10.1073/pnas.1707009114
PMCID: PMC5594678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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