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Article

MicroRNA-132 promotes fibroblast migration via regulating RAS p21 protein activator 1 in skin wound healing

4 Aug 2017

Abstract excerpt

MicroRNA (miR)-132 has been identified as a top up-regulated miRNA during skin wound healing and its inhibition impairs wound repair. In a human in vivo surgical wound model, we showed that miR-132 was induced in epidermal as well as in dermal wound-edge compartments during healing. Moreover, in a panel of cells isolated from human skin wounds, miR-132 was found highly expressed in human dermal fibroblasts...

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PMID: 28798331
DOI: 10.1038/s41598-017-07513-0

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