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Article

High probability and frequency of EGFR mutations in non-small cell lung cancer with brain metastases.

Journal of neuro-oncology - 1 Nov 2017

Ge Mengxi, Zhuang Yingjie, Zhou Xinli, Huang Ruofan, Liang Xiaohua, Zhan Qiong

Abstract excerpt

Lung cancer is the leading cause of cancer death in men and women worldwide. Brain metastasis (BMs) of non-small cell lung cancer (NSCLC) is the most important cause of death. This study aimed to explore the association of epidermal growth factor receptor (EGFR) mutations and BMs in NSCLC. We analyzed 50 NSCLC patients with BMs and 50 match-paired NSCLC patients with no brain metastases (NBMs). The EGFR mutation...

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Identifiers

PMID: 28780743
DOI: 10.1007/s11060-017-2590-x

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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