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Article

Secretome profiles of immortalized dental follicle cells using iTRAQ-based proteomic analysis.

Scientific reports - 4 Aug 2017

Dou Lei, Wu Yan, Yan Qifang, Wang Jinhua, Zhang Yan, Ji Ping

Abstract excerpt

Secretomes produced by mesenchymal stromal cells (MSCs) were considered to be therapeutic potential. However, harvesting enough primary MSCs from tissue was time-consuming and costly, which impeded the application of MSCs secretomes. This study was to immortalize MSCs and compare the secretomes profile of immortalized and original MSCs. Human dental follicle cells (DFCs) were isolated and immortalized using...

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PMID: 28779163
DOI: 10.1038/s41598-017-07467-3
PMCID: PMC5544752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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