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Article

Metachronous colorectal carcinoma with massive submucosal invasion detected by annual surveillance in a Lynch syndrome patient: a case report.

World journal of surgical oncology - 1 Aug 2017

Utsumi Masashi, Tanakaya Kohji, Mushiake Yutaka, Kunitomo Tomoyoshi, Yasuhara Isao, Taniguchi Fumitaka, Arata Takashi, Katsuda Koh, Aoki Hideki, Takeuchi Hitoshi

Abstract excerpt

BACKGROUND: Lynch syndrome is the most common form of hereditary colorectal carcinoma. It is characterized by the presence of germline mutations in DNA mismatch repair genes. Mutation carriers have a lifetime risk of developing colorectal carcinoma of approximately 80%. Current treatment guidelines recommend periodic surveillance for colorectal carcinoma in patients with Lynch syndrome. However, the optimal...

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Source

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Identifiers

PMID: 28764791
DOI: 10.1186/s12957-017-1207-3
PMCID: PMC5540342

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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