Article
A Double-Blind and Placebo-Controlled Trial of Aripiprazole in Symptomatic Youths at Genetic High Risk for Bipolar Disorder.
Journal of child and adolescent psychopharmacology - 1 Dec 2017
Findling Robert L, Youngstrom Eric A, Rowles Brieana M, Deyling Elizabeth, Lingler Jacqui, Stansbrey Robert J, McVoy Molly, Lytle Sarah, Calabrese Joseph R, McNamara Nora K
Abstract excerpt
OBJECTIVE: To determine if acute treatment with aripiprazole (APZ) would be superior to treatment with placebo in reducing dysfunctional symptoms of elevated mood and/or irritability in symptomatic children and adolescents at familial high risk for bipolar disorder (BPD) whose mood episodes occur spontaneously. These are patients we have previously referred to as suffering from "cyclotaxia." METHODS: This was...
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