Article
Two Sides of the Same Coin: Pediatric-Onset and Adult-Onset Common Variable Immune Deficiency.
Journal of clinical immunology - 1 Aug 2017
Sanchez Lauren A, Maggadottir Solrun Melkorka, Pantell Matthew S, Lugar Patricia, Rundles Charlotte Cunningham, Sullivan Kathleen E
Abstract excerpt
PURPOSE: Common variable immunodeficiency (CVID) is a complex, heterogeneous immunodeficiency characterized by hypogammaglobulinemia, recurrent infections, and poor antibody response to vaccination. While antibiotics and immunoglobulin prophylaxis have significantly reduced infectious complications, non-infectious complications of autoimmunity, inflammatory lung disease, enteropathy, and malignancy remain of...
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