Article
NLRP genes and their role in preeclampsia and multi-locus imprinting disorders.
Journal of perinatal medicine - 23 Feb 2018
Soellner Lukas, Kopp Kathrin Maria, Mütze Sabine, Meyer Robert, Begemann Matthias, Rudnik Sabine, Rath Werner, Eggermann Thomas, Zerres Klaus
Abstract excerpt
Preeclampsia (PE) affects 2-5% of all pregnancies. It is a multifactorial disease, but it has been estimated that 35% of the variance in liability of PE are attributable to maternal genetic effects and 20% to fetal genetic effects. PE has also been reported in women delivering children with Beckwith-Wiedemann syndrome (BWS, OMIM 130650), a disorder associated with aberrant methylation at genomically imprinted...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
