Article
Effect of alcohol dehydrogenase-1B and -7 polymorphisms on blood ethanol and acetaldehyde concentrations in healthy subjects with a history of moderate alcohol consumption.
Drug testing and analysis - 1 Mar 2018
Pastorino Roberta, Iuliano Luigi, Vecchioni Alessia, Arzani Dario, Milic Mirta, Annunziata Francesca, Zerbinati Chiara, Capoluongo Ettore, Bonassi Stefano, McKay James D, Boccia Stefania
Abstract excerpt
This study aims to evaluate the effect of ADH1B and ADH7 genotypes on blood acetaldehyde and ethanol levels after alcohol ingestion, and to measure the genotoxic effect of smoking and ethanol on the buccal cells, also controlling for ADH variants. We recruited healthy Italian subjects with at least a moderate history of alcohol consumption. All subjects were given an alcoholic drink of 0.4 g ethanol /kg of body...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.