Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cladosporol A triggers apoptosis sensitivity by ROS-mediated autophagic flux in human breast cancer cells

20 Jul 2017

Abstract excerpt

BACKGROUND: Endophytes have proven to be an invaluable resource of chemically diverse secondary metabolites that act as excellent lead compounds for anticancer drug discovery. Here we report the promising cytotoxic effects of Cladosporol A (HPLC purified >98%) isolated from endophytic fungus Cladosporium cladosporioides collected from Datura innoxia. Cladosporol A was subjected to in vitro cytotoxicity assay...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cell death mechanisms and regulation
Share to Microbial Natural Products and Biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28728544
DOI: 10.1186/s12860-017-0141-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cladosporol A triggers apoptosis sensitivity by ROS-mediated autophagic flux in human breast cancer cellsPMID 28728544Read ↗

Ophiobolin A Induces Autophagy and Activates the Mitochondrial Pathway of Apoptosis in Human Melanoma CellsSemantic proximity Read ↗

Purified Cucurbitacin D leads to alterations of apoptotic and autophagic genes expression in MDA-MB-468 and MCF-7 human breast cancer cellsSemantic proximity Read ↗

Can Some Marine-Derived Fungal Metabolites Become Actual Anticancer Agents?Semantic proximity Read ↗

A novel curcumin-like dienone induces apoptosis in triple-negative breast cancer cellsSemantic proximity Read ↗

Evaluation of Anticancer Activity of Neolamarckia Cadamba Leaves and Its Metabolite ProfileSemantic proximity Read ↗

Achillea fragrantissima (Forssk.) Sch.Bip instigates the ROS/FADD/c-PARP expression that triggers apoptosis in breast cancer cell (MCF-7)Semantic proximity Read ↗

Induction of cellular apoptosis in human breast cancer by DLBS1425, aPhaleria macrocarpacompound extract, via down-regulation of PI3-kinase/AKT pathwaySemantic proximity Read ↗

Reactive Oxygen Species and Autophagy Modulation in Non-Marine Drugs and Marine DrugsSemantic proximity Read ↗

In Vitro Cytotoxicity and Apoptosis Induction in Human Cancer Cells by Culture Extract of an Endophytic Fusarium solani Strain Isolated from Datura metel LSemantic proximity Read ↗

Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cellsSemantic proximity Read ↗

Cytotoxic activity, apoptosis induction and cell cycle arrest in human breast cancer (MCF7) cells by a novel fluorinated tetrahydro-[1,2,4]triazolo[3,4-a]isoquinolin chalconesSemantic proximity Read ↗

Epoxycarotenoids and Cancer. ReviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.