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Article

MicroRNAs as major regulators of the autophagy pathway.

Biochimica et biophysica acta. Molecular cell research - 1 May 2020

Akkoc Yunus, Gozuacik Devrim

Abstract excerpt

Autophagy is a cellular stress response mechanism activation of which leads to degradation of cellular components, including proteins as well as damaged organelles in lysosomes. Defects in autophagy mechanisms were associated with several pathologies (e.g. cancer, neurodegenerative diseases, and rare genetic diseases). Therefore, autophagy regulation is under strict control. Transcriptional and post-translational...

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PMID: 32001304
DOI: 10.1016/j.bbamcr.2020.118662

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