Article
Global outbreak of severe Mycobacterium chimaera disease after cardiac surgery: a molecular epidemiological study.
The Lancet. Infectious diseases - 1 Oct 2017
van Ingen Jakko, Kohl Thomas A, Kranzer Katharina, Hasse Barbara, Keller Peter M, Katarzyna Szafrańska Anna, Hillemann Doris, Chand Meera, Schreiber Peter Werner, Sommerstein Rami, Berger Christoph, Genoni Michele, Rüegg Christian, Troillet Nicolas, Widmer Andreas F, Becker Sören L, Herrmann Mathias, Eckmanns Tim, Haller Sebastian, Höller Christiane, Debast Sylvia B, Wolfhagen Maurice J, Hopman Joost, Kluytmans Jan, Langelaar Merel, Notermans Daan W, Ten Oever Jaap, van den Barselaar Peter, Vonk Alexander B A, Vos Margreet C, Ahmed Nada, Brown Timothy, Crook Derrick, Lamagni Theresa, Phin Nick, Smith E Grace, Zambon Maria, Serr Annerose, Götting Tim, Ebner Winfried, Thürmer Alexander, Utpatel Christian, Spröer Cathrin, Bunk Boyke, Nübel Ulrich, Bloemberg Guido V, Böttger Erik C, Niemann Stefan, Wagner Dirk, Sax Hugo
Abstract excerpt
BACKGROUND: Since 2013, over 100 cases of Mycobacterium chimaera prosthetic valve endocarditis and disseminated disease were notified in Europe and the USA, linked to contaminated heater-cooler units (HCUs) used during cardiac surgery. We did a molecular epidemiological investigation to establish the source of these patients' disease. METHODS: We included 24 M chimaera isolates from 21 cardiac surgery-related...
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