Progressive Atrial Conduction Defects Associated With Bone Malformation Caused by a Connexin-45 Mutation.

doi:10.1016/j.jacc.2017.05.039

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Article

Progressive Atrial Conduction Defects Associated With Bone Malformation Caused by a Connexin-45 Mutation.

Journal of the American College of Cardiology - 18 Jul 2017

Seki Akiko, Ishikawa Taisuke, Daumy Xavier, Mishima Hiroyuki, Barc Julien, Sasaki Ryo, Nishii Kiyomasa, Saito Kayoko, Urano Mari, Ohno Seiko, Otsuki Saki, Kimoto Hiroki, Baruteau Alban-Elouen, Thollet Aurelie, Fouchard Swanny, Bonnaud Stéphanie, Parent Philippe, Shibata Yosaburo, Perrin Jean-Philippe, Le Marec Hervé, Hagiwara Nobuhisa, Mercier Sandra, Horie Minoru, Probst Vincent, Yoshiura Koh-Ichiro, Redon Richard, Schott Jean-Jacques, Makita Naomasa

Abstract excerpt

BACKGROUND: Inherited cardiac conduction disease is a rare bradyarrhythmia associated with mutations in various genes that affect action potential propagation. It is often characterized by isolated conduction disturbance of the His-Purkinje system, but it is rarely described as a syndromic form. OBJECTIVES: The authors sought to identify the genetic defect in families with a novel bradyarrhythmia syndrome...

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PMID: 28705318
DOI: 10.1016/j.jacc.2017.05.039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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