Article
Conserved sequences of BART and BHRF regions encoding viral microRNAs in Epstein-Barr virus-associated lymphoma.
BMC research notes - 14 Jul 2017
Sunagawa Keishin, Hishima Tsunekazu, Fukumoto Hitomi, Hasegawa Hideki, Katano Harutaka
Abstract excerpt
OBJECTIVE: Epstein-Barr virus (EBV) encodes at least 25 pri-microRNAs (miRNAs) in two regions of its DNA genome, BART and BHRF. B95-8, an EBV reference strain, has a deletion in the BART region. However, no information is available on the deletions or mutations in the BART and BHRF regions in clinical samples of EBV-associated lymphoma. RESULTS: Nine DNA fragments encoding miR-BARTs and two coding miR-BHRF1s were...
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