Article
Genetics of Epstein-Barr virus microRNAs.
Seminars in cancer biology - 1 Jun 2014
Klinke Olaf, Feederle Regina, Delecluse Henri-Jacques
Abstract excerpt
The Epstein-Barr virus encodes at least 44 microRNAs that are grouped in two clusters located around the BHRF1 gene and within the BART transcript. The expression pattern of these microRNAs both depends on the lineage of the infected cells and on the type of viral latency. Whilst BART microRNAs are expressed in all EBV-infected tumors, the BHRF1 locus is nearly exclusively expressed in cells that display a type...
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