Article
Type 2 diabetes-associated genetic variants of FTO, LEPR, PPARg, and TCF7L2 in gestational diabetes in a Brazilian population.
Archives of endocrinology and metabolism - 1 Jan 2000
Anghebem-Oliveira Mauren Isfer, Martins Bruna Rodrigues, Alberton Dayane, Ramos Edneia Amancio de Souza, Picheth Geraldo, Rego Fabiane Gomes de Moraes
Abstract excerpt
OBJECTIVE: Gestational diabetes mellitus (GDM) is a metabolic disorder that shares pathophysiologic features with type 2 diabetes mellitus. The aim of this study was to investigate the association of the polymorphisms fat mass and obesity-associated (FTO) rs1421085, leptin receptor (LEPR) rs1137100, rs1137101, peroxisome proliferator-activated receptor gamma (PPARg) rs1801282, and transcription factor 7-like 2...
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