Article
In vitro imaging of bacteria using 18F-fluorodeoxyglucose micro positron emission tomography.
Scientific reports - 10 Jul 2017
Heuker Marjolein, Sijbesma Jürgen W A, Aguilar Suárez Rocío, de Jong Johan R, Boersma Hendrikus H, Luurtsema Gert, Elsinga Philip H, Glaudemans Andor W J M, van Dam Gooitzen M, van Dijl Jan Maarten, Slart Riemer H J A, van Oosten Marleen
Abstract excerpt
Positron emission tomography (PET) with fluorine-18-fluorodeoxyglucose (18F-FDG) can be applied to detect infection and inflammation. However, it was so far not known to what extent bacterial pathogens may contribute to the PET signal. Therefore, we investigated whether clinical isolates of frequently encountered bacterial pathogens take up 18F-FDG in vitro, and whether FDG inhibits bacterial growth as previously...
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