Article
Clinical benefit of sunitinib in gastrointestinal stromal tumors with different exon 11 mutation genotypes.
Future oncology (London, England) - 1 Oct 2017
Dong Zhi, Gao Jing, Gong Jifang, Li Jie, Li Yanyan, Shen Lin, Li Jian
Abstract excerpt
AIM: To assess the efficacy of second-line sunitinib therapy in gastrointestinal stromal tumor patients with different exon 11 mutation genotypes. PATIENTS & METHODS: Thirty eight of the 75 patients received imatinib (IM) dose escalation followed by sunitinib (IM escalation group), while 37 were switched to sunitinib directly after the failure of first-line IM treatment (sunitinib group). Progression-free...
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