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Article

Genetic Mutations and Epigenetic Modifications: Driving Cancer and Informing Precision Medicine.

BioMed research international - 1 Jan 2017

Coyle Krysta Mila, Boudreau Jeanette E, Marcato Paola

Abstract excerpt

Cancer treatment is undergoing a significant revolution from "one-size-fits-all" cytotoxic therapies to tailored approaches that precisely target molecular alterations. Precision strategies for drug development and patient stratification, based on the molecular features of tumors, are the next logical step in a long history of approaches to cancer therapy. In this review, we discuss the history of cancer...

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Identifiers

PMID: 28685150
DOI: 10.1155/2017/9620870
PMCID: PMC5480027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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