Article
Cyclooxygenase-2 (COX-2) polymorphism rs689466 may contribute to the increased susceptibility to post-traumatic osteomyelitis in Chinese population.
Infectious diseases (London, England) - 1 Jan 2000
Wang Lei, Jiang Nan, Lin Qing-Rong, Qin Cheng-He, Hu Yan-Jun, Yu Bin
Abstract excerpt
BACKGROUND: Cyclooxygenase-2 (COX-2) enzyme is one of the major mediators during inflammation reactions, and COX-2 gene polymorphisms of rs20417 and rs689466 have been reported to be associated with several inflammatory diseases. However, potential links between the two polymorphisms and risk of developing post-traumatic osteomyelitis remain unclear. The present study aimed to investigate associations between the...
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