Article
Failure of phylogeny inferred from multilocus sequence typing to represent bacterial phylogeny.
Scientific reports - 3 Jul 2017
Tsang Alan K L, Lee Hwei Huih, Yiu Siu-Ming, Lau Susanna K P, Woo Patrick C Y
Abstract excerpt
Although multilocus sequence typing (MLST) is highly discriminatory and useful for outbreak investigations and epidemiological surveillance, it has always been controversial whether clustering and phylogeny inferred from the MLST gene loci can represent the real phylogeny of bacterial strains. In this study, we compare the phylogenetic trees constructed using three approaches, (1) concatenated blocks of...
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