Article
Optimization of Bartonella henselae multilocus sequence typing scheme using single-nucleotide polymorphism analysis of SOLiD sequence data.
Chinese medical journal - 1 Jul 2012
Zhao Fan, Chaloner Gemma, Darby Alistair, Song Xiu-Ping, Li Dong-Mei, Birtles Richard, Liu Qi-Yong
Abstract excerpt
BACKGROUND: Multi-locus sequence typing (MLST) is widely used to explore the population structure of numerous bacterial pathogens. However, for genotypically-restricted pathogens, the sensitivity of MLST is limited by a paucity of variation within selected loci. For Bartonella henselae (B. henselae), although the MLST scheme currently used has been proven useful in defining the overall population structure of the...
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