Article
Expression and imprinting of DIO3 and DIO3OS genes in Holstein cattle.
Journal of genetics - 1 Jun 2017
Yang Wenzhi, Li Dongjie, Wang Guannan, Wu Xihong, Zhang Mingyue, Zhang Cui, Cui Yali, Li Shijie
Abstract excerpt
DIO3 and DIO3OS are two imprinted genes identified in mouse and humans. The DIO3 gene, which encodes for the type 3 deiodinase, is preferentially expressed from the paternal allele, while the DIO3OS transcript is transcribed in opposite orientation to DIO3, multiple noncoding and alternatively splicing isoforms from maternal allele. In this study, the five splice variants of DIO3OS were identified in Holstein...
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