Delivery of parasite Cdg7_Flc_0990 RNA transcript into intestinal epithelial cells duringCryptosporidium parvuminfection suppresses host cell gene transcription through epigenetic mechanisms

Abstract excerpt

Cryptosporidial infection causes dysregulated transcription of host genes key to intestinal epithelial homeostasis, but the underlying mechanisms remain obscure. Previous studies demonstrate that several Cryptosporidium parvum (C. parvum) RNA transcripts are selectively delivered into epithelial cells during host cell invasion and may modulate gene transcription in infected cells. We report here that C. parvum...

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