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Article

Variants of the ABCA3 gene might contribute to susceptibility to interstitial lung diseases in the Chinese population.

Scientific reports - 22 Jun 2017

Zhou Wei, Zhuang Yi, Sun Jiapeng, Wang Xiaofen, Zhao Qingya, Xu Lizhi, Wang Yaping

Abstract excerpt

ATP-binding cassette A3 (ABCA3) is a phospholipid carrier that is mainly expressed in the alveolar epithelium. Biallelic mutations of ABCA3 has been associated with fatal respiratory distress syndrome and interstitial lung disease (ILD) in children. However, whether variations in ABCA3 have a role in the development of adult ILD, including idiopathic pulmonary fibrosis (IPF), remains to be addressed. In this...

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Source

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Identifiers

PMID: 28642621
DOI: 10.1038/s41598-017-04486-y
PMCID: PMC5481373

Genes

ABCA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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