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Article

The Accuracy and Bias of Single-Step Genomic Prediction for Populations Under Selection.

G3 (Bethesda, Md.) - 7 Aug 2017

Hsu Wan-Ling, Garrick Dorian J, Fernando Rohan L

Abstract excerpt

In single-step analyses, missing genotypes are explicitly or implicitly imputed, and this requires centering the observed genotypes using the means of the unselected founders. If genotypes are only available for selected individuals, centering on the unselected founder mean is not straightforward. Here, computer simulation is used to study an alternative analysis that does not require centering genotypes but fits...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28642364
DOI: 10.1534/g3.117.043596
PMCID: PMC5555473

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