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Validation with single-step SNPBLUP shows that evaluations can continue using a single mean of genotyped individuals, even with multiple breeds.

Genetics, selection, evolution : GSE - 22 Mar 2023

Aldridge Michael, Vandenplas Jeremie, Duenk Pascal, Henshall John, Hawken Rachel, Calus Mario

Abstract excerpt

BACKGROUND: In genomic prediction, it is common to centre the genotypes of single nucleotide polymorphisms based on the allele frequencies in the current population, rather than those in the base generation. The mean breeding value of non-genotyped animals is conditional on the mean performance of genotyped relatives, but can be corrected by fitting the mean performance of genotyped individuals as a fixed...

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PMID: 36949392
DOI: 10.1186/s12711-023-00787-1
PMCID: PMC10031914

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