Article
MiR-646 inhibited cell proliferation and EMT-induced metastasis by targeting FOXK1 in gastric cancer.
British journal of cancer - 8 Aug 2017
Zhang P, Tang W M, Zhang H, Li Y Q, Peng Y, Wang J, Liu G N, Huang X T, Zhao J J, Li G, Li A M, Bai Y, Chen Y, Ren Y X, Li G X, Wang Y D, Liu S D, Wang J D
Abstract excerpt
BACKGROUND: MiR-646 has been reported to be aberrantly expressed in human cancers. However, the underlying molecular mechanisms of action of miR-646 in gastric cancer (GC) have not yet been investigated. METHODS: In vitro function of miR-646 in GC was evaluated using EdU assay, plate colony formation assay, and matrigel invasion assay. Real-time PCR or western blotting was performed to detect miR-646 and FOXK1...
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