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Article

Is the atopic march related to confounding by genetics and early-life environment? A systematic review of sibship and twin data.

Allergy - 1 Jan 2018

Khan S J, Dharmage S C, Matheson M C, Gurrin L C

Abstract excerpt

A popular hypothesis known as the atopic march proposes a set of sequential allergy and respiratory disorders in early childhood contributes enormously to the burden of disease in developed countries. Although the concept of the atopic march has been refined and strengthened by many cross-sectional and longitudinal studies linking eczema as the initial manifestation with progression to hay fever and then asthma,...

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PMID: 28618023
DOI: 10.1111/all.13228

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