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Article

A novel iterative mixed model to remap three complex orthopedic traits in dogs.

PloS one - 1 Jan 2017

Huang Meng, Hayward Jessica J, Corey Elizabeth, Garrison Susan J, Wagner Gabriela R, Krotscheck Ursula, Hayashi Kei, Schweitzer Peter A, Lust George, Boyko Adam R, Todhunter Rory J

Abstract excerpt

Hip dysplasia (HD), elbow dysplasia (ED), and rupture of the cranial (anterior) cruciate ligament (RCCL) are the most common complex orthopedic traits of dogs and all result in debilitating osteoarthritis. We reanalyzed previously reported data: the Norberg angle (a quantitative measure of HD) in 921 dogs, ED in 113 cases and 633 controls, and RCCL in 271 cases and 399 controls and their genotypes at ~185,000...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28614352
DOI: 10.1371/journal.pone.0176932
PMCID: PMC5470659

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