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Article

Maternal and Early-Life Circadian Disruption Have Long-Lasting Negative Consequences on Offspring Development and Adult Behavior in Mice.

Scientific reports - 12 Jun 2017

Smarr Benjamin L, Grant Azure D, Perez Luz, Zucker Irving, Kriegsfeld Lance J

Abstract excerpt

Modern life involves chronic circadian disruption through artificial light and these disruptions are associated with numerous mental and physical health maladies. Because the developing nervous system is particularly vulnerable to perturbation, we hypothesized that early-life circadian disruption would negatively impact offspring development and adult function. Pregnant mice were subjected to chronic circadian...

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Identifiers

PMID: 28607386
DOI: 10.1038/s41598-017-03406-4
PMCID: PMC5468226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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