Article
Disruption of paternal circadian rhythm affects metabolic health in male offspring via nongerm cell factors.
Science advances - 1 May 2021
Lassi Maximilian, Tomar Archana, Comas-Armangué Gemma, Vogtmann Rebekka, Dijkstra Dorieke J, Corujo David, Gerlini Raffaele, Darr Jonatan, Scheid Fabienne, Rozman Jan, Aguilar-Pimentel Antonio, Koren Omry, Buschbeck Marcus, Fuchs Helmut, Marschall Susan, Gailus-Durner Valerie, Hrabe de Angelis Martin, Plösch Torsten, Gellhaus Alexandra, Teperino Raffaele
Abstract excerpt
Circadian rhythm synchronizes each body function with the environment and regulates physiology. Disruption of normal circadian rhythm alters organismal physiology and increases disease risk. Recent epidemiological data and studies in model organisms have shown that maternal circadian disruption is important for offspring health and adult phenotypes. Less is known about the role of paternal circadian rhythm for...
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