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Article

Female-specific association of NOS1 genotype with white matter microstructure in ADHD patients and controls.

Journal of child psychology and psychiatry, and allied disciplines - 1 Aug 2017

van Ewijk Hanneke, Bralten Janita, van Duin Esther D A, Hakobjan Marina, Buitelaar Jan K, Heslenfeld Dirk J, Hoekstra Pieter J, Hartman Catharina, Hoogman Martine, Oosterlaan Jaap, Franke Barbara

Abstract excerpt

BACKGROUND: The nitric oxide synthase gene (NOS1) exon 1f (ex1f) VNTR is a known genetic risk factor for Attention-Deficit/Hyperactivity Disorder (ADHD), particularly in females. NOS1 plays an important role in neurite outgrowth and may thus influence brain development, specifically white matter (WM) microstructure, which is known to be altered in ADHD. The current study aimed to investigate whether NOS1 is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28589541
DOI: 10.1111/jcpp.12742
PMCID: PMC5513773

Genes

NOS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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