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Article

Differential expression analysis at the individual level reveals a lncRNA prognostic signature for lung adenocarcinoma

6 Jun 2017

Abstract excerpt

Deregulations of long non-coding RNAs (lncRNAs) have been implicated in cancer initiation and progression. Current methods can only capture differential expression of lncRNAs at the population level and ignore the heterogeneous expression of lncRNAs in individual patients. We propose a method (LncRIndiv) to identify differentially expressed (DE) lncRNAs in individual cancer patients by exploiting the disrupted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28587642
DOI: 10.1186/s12943-017-0666-z

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