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Inspecting Targeted Deep Sequencing of Whole Genome Amplified DNA Versus Fresh DNA for Somatic Mutation Detection: A Genetic Study in Myelodysplastic Syndrome Patients.

Biopreservation and biobanking - 1 Aug 2017

Palomo Laura, Fuster-Tormo Francisco, Alvira Daniel, Ademà Vera, Armengol María Pilar, Gómez-Marzo Paula, de Haro Nuri, Mallo Mar, Xicoy Blanca, Zamora Lurdes, Solé Francesc

Abstract excerpt

Whole genome amplification (WGA) has become an invaluable method for preserving limited samples of precious stock material and has been used during the past years as an alternative tool to increase the amount of DNA before library preparation for next-generation sequencing. Myelodysplastic syndromes (MDS) are a group of clonal hematopoietic stem cell disorders characterized by presenting somatic mutations in...

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PMID: 28586236
DOI: 10.1089/bio.2016.0094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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