Article
Genome-scale identification of microRNA-related SNPs associated with risk of head and neck squamous cell carcinoma.
Carcinogenesis - 1 Oct 2017
Wilkins Owen M, Titus Alexander J, Gui Jiang, Eliot Melissa, Butler Rondi A, Sturgis Erich M, Li Guojun, Kelsey Karl T, Christensen Brock C
Abstract excerpt
Polymorphisms in microRNAs and their target sites can disrupt microRNA-dependent gene regulation, and have been associated with cancer susceptibility. However, genome-scale analyses of microRNA-related genetic variation in cancer are lacking. We tested the associations of ~40 000 common [minor allele frequency (MAF) ≥5%], microRNA-related single nucleotide polymorphisms (miR-SNPs), with risk of head and neck...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
