Article
In vitro site-specific recombination mediated by the tyrosine recombinase XerA of Thermoplasma acidophilum.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Jul 2017
Jo Minji, Murayama Yasuto, Tsutsui Yasuhiro, Iwasaki Hiroshi
Abstract excerpt
In organisms with circular chromosomes, such as bacteria and archaea, an odd number of homologous recombination events can generate a chromosome dimer. Such chromosome dimers cannot be segregated unless they are converted to monomers before cell division. In Escherichia coli, dimer-to-monomer conversion is mediated by the paralogous XerC and XerD recombinases at a specific dif site in the replication termination...
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