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Article

A three‐gene signature from protein–protein interaction network of LOXL 2‐ and actin‐related proteins for esophageal squamous cell carcinoma prognosis

29 May 2017

Abstract excerpt

Current staging is inadequate for predicting clinical outcome of esophageal squamous cell carcinoma (ESCC). Aberrant expression of LOXL2 and actin-related proteins plays important roles in ESCC. Here, we aimed to develop a novel molecular signature that exceeds the power of the current staging system in predicting ESCC prognosis. We found that LOXL2 colocalized with filamentous actin in ESCC cells, and gene set...

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PMID: 28556501
DOI: 10.1002/cam4.1096

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